Reactive hyperemia
Cuff occlusion and release creates increased blood flow response.
Product overview
ENDogram clinical workflow
A body of medical literature exists which suggests that abnormal endothelial function is associated with atherosclerosis. Further, it has been established that endothelial function can be evaluated by observing hemodynamics in the hyperemic phase.
The Endogram works by occluding blood flow in the arm and then gauging the post-ischemic pulsatile component of flow and the artery's largest volume change. The dilation of the arterial segment is correlated with endothelial function, which is believed to be an early indicator of CAD.
The arterial wall is composed of four circular structures. The structure in contact with blood in the arteries is called the endothelium. Healthy endothelium releases nitric oxide when local blood flow increases, helping small arteries dilate and increasing blood flow at a reduced workload for the heart.
In diseased endothelium, increased local blood flow does not release adequate nitric oxide, and the response in arterial dilation and blood flow is blunted. The device measures the pulsatile component of flow before dilation, immediately after cuff release, and until flow returns to pre-occlusion levels.
The patented ENDogram technology received FDA approval for marketing while implemented in Model 300 as a standalone product and is positioned as part of the integrated Vascular Diagnostic Center.
01Baseline pulsatile flow captured before occlusion.
02Arm cuff occludes blood flow to create reactive hyperemia.
03Post-ischemic pulsatile component of flow is measured.
04Response pattern supports endothelial function assessment.
Readable product data
Clinical information rebuilt as HTML
The old screenshot-style material has been translated into clean cards, flows and data panels so users can read the product value clearly.
Qp measurement
Measures pulsatile component of flow before and after release.
Endothelial response
Dilation pattern supports endothelial function evaluation.
Clinical indicator
Endothelial dysfunction may be an early CAD indicator.
Documents & evidence
Product files and supporting material
PDFs, forms, brochures, FDA documentation and publications are available for customer review.
Intellectual property, forms & brochures
USFDA 510(k) Approval LettersPDFVasogram Patient Tracking FormPDFPatient Intake FormPDFPADogram Cuff Placement FormPDFABIgram Cuff Placement FormPDFVasogram Cuff Placement FormPDFMarketing Brochure — Inside PagePDFMarketing Brochure — Outside PagePDFInterCare Vascular Diagnostic Center Brochure — InsidePDFInterCare Vascular Diagnostic Center Brochure — OutsidePDFInterCare Vascular Diagnostic Center PosterPDF